Oct 14, 2018
Our long awaited special 50th episode where we delve into the bigger picture while discussing many topics including the biochemistry of cholesterol & statins, the scientific method, philosophy, processed foods and top it off with a dose of what we can learn from evolution and how to lead a fulfilling life. This one is a GREAT episode!
After obtaining a degree from the University of Leeds in English
and Philosophy, Nick Mailer co-authored the first book in the UK on
the education possibilities of the Internet. He co-founded The
Positive Internet Company, UK's premier open-source managed
services organisation. He also founded the Campaign for Unmetered
He has spoken at conferences, including the Ancestral Health Symposium and Ketofest, on the nexus of culture, technology and semiotics. Since 2010, he has adopted a paleo-ish LCHF lifestyle, to which he nevertheless applies a multidisciplinary scepticism! He lives in London with his wife, daughter and cat.
0:15 - Epic Superhero Intro
9:13 - How did you get into Low Carb?
14:23 - A philosophical perspective, paradoxes and the impracticality of certain scientific models
18:40 - How different people handle paradoxes to their knowledge
20:55 - Will we get the next Galileo or Einstein in the world of science and research?
24:38 - Paradigm shifts in modern science and repeating human patterns when confronted with conflicting knowledge
29:26 - Meaning of a statement may be a method of of its verification
32:25 - What is a "Black Swan", Cholesterol and the narrative of the Kitavans
37:15 - PURE study and what knowledge you can obtain from observational studies
39:09 - Mevalonate pathway, statins and the importance of simplifying and understanding science
44:30 - The role of cholesterol, how statins disrupt the body's mechanisms and the impact of statins on a cellular level
47:51 - Why anyone can now obtain knowledge and should embrace complexity and details
52:00 - Concerns when people outsource critical thinking on social media forums and groups
55:42 - Pros and cons of deferring to an authority and how to ground yourself in a sea of too much information
1:06:05 - Difference between the pleasure of eating and the pain of eating
1:12:08 - Human adaptations, homeostatic mechanisms, hormones and brain rewards
1:16:15 - Thinking of & troubleshooting the body as a slowly self-learning software
1:21:20 - Why using food processing in a negative connotation is a limited way of thinking
1:24:35 - A discussion about sweeteners: erythritol and aspartame
1:28:33 - The benefit of not nuking your palate with sweeteners
1:34:46 - The bigger picture, living a happy life and lessons we can obtain from evolution
1:45:44 - Final Plugs